Haemoglobin A1 and diabetes.

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haemoglobin alc bedutung bei diabetes mellitus

blood specimens from 22 insulin dependent diabetic patient and 17 nontliabetic subject were collected im edta- tubes. quantitation of hb-al was performed by columne chromatography. the glycosylated hemoglobin component is increased in diabetic patient and found a significant correlation between hb-al concentration and blood glucose levels in all diabetic patients. the mean hb-al valve for diabe...

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Routine measurement of haemoglobin A1 at the diabetic outpatient clinic.

FOLLOWING the introduction of insulin therapy in 1922 one of the major problems in the long-term management of insulin-dependent diabetes was the lack of a convenient, reliable and objective test of longer term glycaemic control. In the 1960's and early 1970's haemoglobin A, (HbA,, glycosylated haemoglobin) was shown to be elevated, usually, in diabetic patients 1-3 and its biochemical structur...

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Haemoglobin O Padova and falsely low haemoglobin A1c in a patient with type I diabetes.

Glycated haemoglobin (HbA1c) measured by high performance liquid chromatography (HPLC) in a 20 year old female with insulin dependent diabetes mellitus was consistently within the normal range although her daily blood glucose values were > 11.1 mmol/l. HbA1c measured by immunoagglutination and fructosamine was elevated and correlated with the patient's blood glucose values. The HPLC chromatogra...

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OBJECTIVES The oral glucose tolerance test (OGTT) is a cumbersome test that is time consuming, labour intensive and often poorly tolerated by pregnant women. To date, glycosylated haemoglobin (HbA1c) is the most accepted measure of chronic glycaemia outside of pregnancy. HbA1c is an uncomplicated test, less time consuming, does not require any specific patient preparation and is considered stra...

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ژورنال

عنوان ژورنال: BMJ

سال: 1981

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.282.6258.149-b